top of page

How Gratitude Changes Your Brain (Even When Life Sucks)

August 17, 2026

Erica Anderson Rooney
Erica Rooney smiling with a microphone in hand

Hey there!
I'm Erica Rooney

I'm an ex corporate girl, turned founder, and 2x bestselling author, and I help women get into positions of power - and STAY there - without burning out.

Find me elsewhere:

Instagram

Facebook

LinkedIn

YouTube

TikTok

  • Instagram
  • Facebook
  • LinkedIn
  • YouTube
  • TikTok

How Gratitude Changes Your Brain (Even When Life Sucks)

It is the one week of the year when everybody performs gratitude. Now think about the year you are actually having. Because gratitude is easy when you just landed the new position or got the raise, and close to impossible when you are watching layoffs land right before the holidays, or facing a scary diagnosis, or sitting in the middle of a divorce.


Here is the part that surprised me. A regular practice of gratitude does not just make you feel better. It quite literally changes the chemistry of your brain. People who consistently feel and express gratitude show higher volumes of gray matter. Gratitude wires and fires new neural connections into the reward center of the brain, it evokes positive thinking, and it reduces fear and anxiety by regulating the stress hormone.


The research here has real names attached to it. Joel Wong and Joshua Brown at Indiana University studied people already receiving counseling for depression and anxiety. One group wrote and delivered a single letter of gratitude to someone who had made a difference in their life. Brain scans taken three months later still showed changes in the prefrontal cortex and reduced activity in the regions tied to anxiety, from that one exercise. The Mindful Awareness Research Center at UCLA has reported the same direction of travel, that gratitude changes the neural structures that shape how we see the world and how we see ourselves.


Think of it like a path through the woods. The path everybody walks every day is worn down and easy to follow, so of course you take it when you see it. If you are not naturally a grateful person and you have not been practicing, your gratitude path is covered in vines and rocks and brush. The only thing that widens it is walking it. So start whacking those trees down and clearing the brush. That is the entire practice.


When I was really stuck in my sticky floor, when I was having issues in my marriage and I was not happy in my job, I woke up every single day, picked up a plain notebook, and made myself write out three things I was grateful for. Some days the only three I could muster were that I was breathing, which meant I was alive, that I could read and write at all when not everyone can, and that I had a roof over my head. That was it. And the days that were hardest turned out to be exactly the days I needed it most.


Gratitude is not a magic bullet. It will not make your problems disappear, it will not cure sadness or depression, and it will not stop the pain you may be going through. Think of it instead as part of your resilience arsenal, the thing you reach for to remember that you have survived 100% of your bad days. My favorite line still holds. The beauty of uncertainty is infinite possibility. And I am genuinely, from the bottom of my heart, grateful for you.

TRANSCRIPT:

Erica: Hey, girl. By now, you know I have Her Collective, my online community for ambitious women who are done doing it alone. Her Collective is for the women who are smart, capable, and driven, but they find themselves stuck on the sticky floors like self doubt, burnout, and waiting for permission that quite honestly never comes. Inside HER, you get more than motivation. You get real support, real strategies, and real momentum. We work on things like clarifying what you want now and what's coming next, building confidence without burning yourself out, navigating hard conversations, career moves, and leadership moments with clarity, and surrounding yourself with women who actually get it. This isn't about hustling harder. It's about moving intentionally with the right tools and the right people in your corner. If you're ready to stop spinning, start choosing yourself, and build a career in life that actually feels aligned, I'd love to welcome you inside her collective. You can learn more and join us at www.joinhercollective.com. Because honestly, girl, you were never meant to do this alone. Did you know that a regular practice of gratitude can quite literally change the chemistry in your brain. Happy Thanksgiving week. I'm your host, Erica Rooney. We are full on into that one week of the year where everybody is expressing their gratitude, their appreciation, their thankfulness for their health, their families, their careers, but it's not always easy to be grateful. Not when we're headed into this recession with thousands of people losing their jobs right before the holiday. There are people who are out there battling scary health diagnoses, the loss of family members, people in the midst of divorce. And gratitude just seems impossible. It is much easier to be grateful when life is on the up and up. When you've landed that new position, you've gotten a raise, you've gotten engaged, you know, you've watched your kids do something amazing. But what about when life sucks? When you're at your wit's end? When you're feeling just hopeless? Now that's where the practice of gratitude really needs to come in, and it is needed the most. In positive psychology, psychologists have defined gratitude as that positive emotion that we perceive when giving or receiving a benefit from someone or something. When we thank others, when we thank ourselves, the universe, whatever higher power app be, it actually has a healing effect. The benefits of gratitude are endless. It's been shown to make you happier, giving you an enhanced mood, make you more aware. It improves your physical health by helping you sleep better, a stronger immune system, less aches and pains, and even, you guys, optimum blood pressure. Hello, if there hasn't been a reason to be grateful, it is to keep our hearts in check. But people who are grateful tend to have more empathy, they are better communicators, and they have stronger interpersonal relationships. And that makes you a better leader. Gratitude quite literally has the power to rewire your brain. So, it's been found that people who express and feel gratitude have this higher volume of gray matter. Now there's a whole bunch of brain jargon in there that doesn't exactly jive with my HR executive coach brain. But when I read through the study, it found that gratitude wires and fires new neural connection to the bliss center of the brain. It fosters a cognitive restructuring by evoking positive thinking and reduces fear and anxiety by regulating the stress hormone. It also enhances the neurotransmitters responsible for happiness. When we get into the practice of consciously expressing gratitude every day, we help these neural pathways to strengthen themselves and ultimately create a permanent, grateful, and positive nature within ourselves. Now, I want you to think of this like a path in the woods. That path that everybody takes every single day is worn down. It's easy to follow. If you walked up to the woods and you saw that path, you would take it, right? If you are not naturally a grateful person and you have not been practicing gratitude, your path is not going to be worn like that. It's going to be covered in vines, rocks, trees, brush, who knows what. Okay? But the more you take it, the more that path becomes visible. It becomes wider. It becomes easier to walk down. So, start doing that every single day. Start whacking those trees down, clearing the brush so that gratitude becomes that permanent, positive nature. The Mindfulness Awareness Research Center of UCLA stated that gratitude does change those neural structures of our brain. It makes us happier. It makes us more content. And when we activate the reward center of our brain, gratitude exchange alters the way that we see the world and how we see ourselves. So scientists in 2,008 conducted a study to actually measure the brain activity of people thinking and feeling gratitude. And what they found was that gratitude caused synchronized activation in multiple brain regions, lighting up parts of our brains that reward center, right? And also the hypothalamus. Meaning, that gratitude can boost neurotransmitter called serotonin and activate the brain to produce dopamine. And guys, dopamine is our brain's pleasure chemical. We always want more of it. That's why we're reaching for the treats. That's why we do the things that make us feel good. Because dopamine is released. So, the more we think positive, grateful thoughts, the happier and healthier we feel. Now, one thing that's really cool to think about is our brain is very flexible. It can mold, it can change. So, that positive thinking, that regular practice of gratitude can become a way of life when you make it a habit. When your brain is constantly flushed with positive thoughts, you can expect to improve in every area of your life, in relationships, in your health, performance at work, reaching your goals, hitting new milestones. Literally, everywhere. Gratitude though, we all know it's not a magic bullet. If you are really going through it, you're not going to be able to just sit down and think about all these grateful thoughts and have all of your problems just disappear. It's not going to cure your feelings of sadness or depression and it's not going to stop all of the pain that you may be going through. But I want you to think of gratitude as a piece of resilience arsenal. Think of it as something that you can rely on to help you out of those hard times. You guys, when I was really stuck in my sticky floor, when I was going through it, having issues in my marriage and just not happy with my job, every single day, I would wake up, I would pick up just a plain notebook, and I would make myself write out at least three things that I was grateful for. Those three things could sometimes be as simple as I was grateful to be breathing. It meant I was alive. I was grateful that I could write in the journal because not everybody has the skill of writing and reading. I was grateful for the roof over my head. Sometimes, those were the only three things that I could muster up being grateful for. And as I practice that, I could add in more. And I found that on the days that were really hard, those are the days I needed it most. And I would try to make myself come up with as many things that I could be grateful for as possible. When we can find moments of gratitude we become more resilient. We know that this too shall pass. We understand that we have survived 100% of our bad days. We know that we will bounce back. When we are grateful, we know that if we are being laid off from a job, it's only opening the other door of opportunity. And y'all know my favorite quote from Toon Day is the beauty of uncertainty is infinite possibility. When you feel stuck in this feeling of uncertainty, find gratitude in knowing that there is infinite possibility on the other side. So, with all of this in mind, I am so very grateful for you, friend. I am grateful for your support, for your downloads. Six months ago, I don't think that I could've imagined that I would be in this place today but because of you, I am. So, thank you. From the bottom of my heart, thank you. I hope you have an amazing Thanksgiving. And this Thanksgiving week, I am so thankful to also share with you my ebook, level up your LinkedIn content kit. If you're not sure what to post this this Thanksgiving on your LinkedIn, what's too personal, what's not personal enough, if you're not sure how to post in a way that will help you gain meaningful and valuable connections that will help you grow your network and land your next level role. You need to download this book right away. I am not kidding. This is a quick and easy read. It will give you instant results to literally 10 x your network. Don't wait. Download it today. The link is in the show notes. And as always, rate, review, and subscribe to the show as it helps those who need to hear it see it first. Have a great Thanksgiving.

​RESOURCES MENTIONED IN THIS EPISODE:

- Ready to stop spinning and stop doing it alone? Join HER Collective, Erica's community for ambitious women who are smart, capable and driven.

- Never miss an episode of Glass Ceilings & Sticky Floors.

- Get Erica's book Glass Ceilings and Sticky Floors and start shattering the beliefs that keep you stuck.

- The Mindful Awareness Research Center at UCLA, on how gratitude changes the brain.

- How Gratitude Changes You and Your Brain by Joel Wong and Joshua Brown, Greater Good Magazine.

- The seven-day gratitude challenge.

RELATED EPISODES:

I Paused This Recording to Yell at My Kids

The Joy Journal: How Happiness Expert Jessica Weiss Rewires Your Brain in Just 14 Days

Put a Finger Down If You've Ever Beaten Yourself Up

FREQUENTLY ASKED QUESTIONS:

How does gratitude change your brain?

Gratitude fires new neural connections toward the brain's reward center, boosts serotonin and dopamine, and helps regulate the stress hormone behind fear and anxiety. People who regularly feel gratitude show higher volumes of gray matter. Joel Wong and Joshua Brown at Indiana University found that brain scans still showed changes in the prefrontal cortex three months after participants wrote a single gratitude letter.


How do you practice gratitude when life is genuinely hard?

Erica's method is a plain notebook and three things every morning, no matter how small they are. During the hardest stretch of her life the three were that she was breathing, that she could read and write, and that she had a roof over her head. She is clear that the hard days are exactly the days the practice matters most.


Is gratitude a cure for depression or anxiety?

No, and Erica says so plainly. Gratitude will not make your problems disappear and it will not cure sadness or depression. She frames it as one item in your resilience arsenal, something to lean on to get through hard times rather than a replacement for real help.

MORE FROM ME

Follow me on Instagram @ericaandersonrooney and @joinhercollective

SUBSCRIBE & REVIEW

If you loved this episode, please take a moment to subscribe and leave a review on Apple Podcasts. Your support helps us reach more women who need these insights. Thank you for tuning in to the Glass Ceilings and Sticky Floor podcast. See you next week!

Hi, I'm Erica!

In the last 15 years, I climbed to Chief People Officer, 6x'd my income, walked away from a culture that stopped matching my values, wrote two books, and built HER Collective to help thousands of women rise to power and lead in the age of AI. I've learned a thing or two about smashing ceilings and closing gaps, and Glass Ceilings & Sticky Floors is where I open the playbook, the receipts, and the real stories to share it all with you.

Erica Rooney in a pink vest, holding a microphone in front of a director's chair with a podcast mic and her two books, The AI Gap and Glass Ceilings & Sticky Floors, smiling
  • Instagram
  • Facebook
  • LinkedIn
  • YouTube
  • TikTok

919-609-9419

©2026 by ERA Advisors.

bottom of page